【关键词】血清同型半胱氨酸；C反应蛋白；白细胞；冠心病；诊断效果；确诊率
[Abstract] Objective: To observe the effect and value of homocysteine uniting with C reactive protein and white blood cell in the in patients with coronary heart disease. Method: Selecting 91 cases of coronary heart disease in the hospital from January 2015 to June 2016, they are set to be the observation group. Among them, acute myocardial infarction in 25 cases, unstable angina pectoris in 24 cases, and stable angina pectoris in 22 cases. In the same period, 33 patients admitted to hospital were selected as control group. Enzyme assay was used to detect Hcy, and CRP level was measured by immune scatter turbidity method, Using XE-5000 automatic blood analyzer to measure the level of WBC in the two groups, to analyze the diagnostic effect of Hcy combined with CRP and WBC in patients with coronary heart disease. Results: The levels of CRP combined with WBC and Hcy in the observation group were significantly higher than those in the control group (P<0.05); Acute myocardial infarction, unstable angina and stable angina pectoris Hcy combined with CRP and WBC levels were higher than those in the control group (P<0.05); Hcy combined with CRP and WBC levels in patients with acute myocardial infarction was significantly higher than that in patients with unstable angina and stable angina pectoris (P<0.05); Hcy index ROC curve area was 0.84, CRP index ROC curve area was 1 and WBC index ROC curve area was 0.96. Conclusion: the diagnosis effect of coronary heart disease patients using Hcy combined with CRP and WBC is ideal, and it can improve the clinical diagnosis rate, so it is worth popularizing.
[Key words] serum homocysteine; C reactive protein; white blood cell; coronary heart disease; diagnosis effect; diagnosis rate
冠心病（coronary heart disease，CHD）是由于冠状动脉发展粥样硬化使得管腔狭窄或阻塞等，导致心肌缺血、缺氧等引起的心脏病。患者发病后病理变化进展相对较慢，病情较轻者临床上缺乏特异性症状，病情较重者，将会引起心肌梗塞及猝死等，影响患者健康[1]。目前，临床上对于冠心病主要以冠状动脉造影诊断为主，且该方法一度被认为是冠心病的“金标准”[2]。但是，冠状动脉造影检查属于是一种有创检查，检查费用相对较高，导致患者检查依从性较差。因此，积极寻找一种简便、易行、无创性检查方法对提高临床确诊率具有重要的意义。近年来，Hc）联合CRP及WBC在冠心病患者中得到应用，且效果理想[3]。为了探讨血清同型半胱氨酸（Hcy）联合C反应蛋白（CRP）及白细胞（WBC）在冠心病患者中的诊断效果及价值。选取2015年1月-2016年6月医院诊治的冠心病患者60例，报道如下。
1.资料与方法
1.1临床资料
1.2 方法
1.3 观察指标
2.结果
2.1 检测四个指标在各组中的差异性
2.2 Hcy联合CRP及WBC水平ROC曲线面积比较
3.讨论
【参考文献】
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